Insulin 抗体
Quick Overview for Insulin 抗体 (ABIN7467892)
抗原
See all Insulin (INS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Affinity purified by Protein A.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human C-Peptide. The exact sequence is proprietary.
-
亚型
- IgG2b
-
-
-
-
应用备注
- ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.82 mg/mL
-
缓冲液
- PBS, No Preservative
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- Insulin (INS)
-
别名
- insulin
-
背景
- INS Antibody , insulin Antibody , IRDN Antibody , IDDM2 Antibody , MODY10 Antibody , ILPR Antibody,After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]
-
分子量
- 12 kDa
-
基因ID
- 3630
-
途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
-