HLA-DQB1 抗体
-
- 抗原 See all HLA-DQB1 抗体
- HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HLA-DQB1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human HLA-DQB1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product HLA-DQB1 Primary Antibody
-
anti-Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1) (AA 128-175) antibody
HLA-DQB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1) (AA 1-261) antibodyHLA-DQB1 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1) (AA 129-217) antibodyHLA-DQB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1) (AA 1-261) antibodyHLA-DQB1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1) (AA 13-39), (N-Term) antibodyHLA-DQB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
-
Positive Control: Jurkat
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.7 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- 抗原
- HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1))
- 别名
- major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1 产品)
- 别名
- CELIAC1 antibody, HLA-DQB antibody, IDDM1 antibody, mhc-DRB antibody, DLA-DQB antibody, MAMU-DQB1 antibody, LOC100172120 antibody, DKFZp469C0237 antibody, major histocompatibility complex, class II, DQ beta 1 antibody, HLA-DQB1 antibody, PATR-DQB1 antibody, DLA-DQB1 antibody, MAMU-DQB1 antibody, LOC100172120 antibody
- 背景
- Major histocompatibility complex, class II, DQ beta 1 , CELIAC1 , HLA-DQB , IDDM1,HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
- 分子量
- 30 kDa
- 基因ID
- 3119
- UniProt
- P01920
- 途径
- TCR Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
-
