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Caspase 9 抗体 (C-Term, Cleaved-Asp330)

This anti-Caspase 9 antibody is a 兔 多克隆 antibody detecting Caspase 9 in WB. Suitable for 人.
产品编号 ABIN7464674
发货至: 中国

Quick Overview for Caspase 9 抗体 (C-Term, Cleaved-Asp330) (ABIN7464674)

抗原

See all Caspase 9 (CASP9) 抗体
Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

适用

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宿主

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克隆类型

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多克隆

标记

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This Caspase 9 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term, Cleaved-Asp330

    交叉反应

    人, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Caspase 9 (cleaved Asp330). The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Jurkat (10 μM Etoposide treatment for 24 hr)

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.73 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

    别名

    caspase 9

    背景

    Caspase 9 , APAF-3 , APAF3 , ICE-LAP6 , MCH6 , PPP1R56,This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

    分子量

    46 kDa

    基因ID

    842

    UniProt

    P55211

    途径

    MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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