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FGFR1 抗体 (pTyr766)

This anti-FGFR1 antibody is a 兔 多克隆 antibody detecting FGFR1 in WB. Suitable for 人.
产品编号 ABIN7464374
发货至: 中国

Quick Overview for FGFR1 抗体 (pTyr766) (ABIN7464374)

抗原

See all FGFR1 抗体
FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

适用

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克隆类型

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多克隆

标记

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This FGFR1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pTyr766

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide surrounding phospho Tyr766 of human FGFR1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A549

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.75 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

    别名

    fibroblast growth factor receptor 1

    背景

    Fibroblast growth factor receptor 1 , BFGFR , CD331 , CEK , ECCL , FGFBR , FGFR-1 , FLG , FLT-2 , FLT2 , HBGFR , HH2 , HRTFDS , KAL2 , N-SAM , OGD , bFGF-R-1,The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. [provided by RefSeq]

    分子量

    92 kDa

    基因ID

    2260

    UniProt

    P11362

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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