电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Presenilin 2 抗体 (AA 275-325)

This anti-Presenilin 2 antibody is a 兔 多克隆 antibody detecting Presenilin 2 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7455024
发货至: 中国

Quick Overview for Presenilin 2 抗体 (AA 275-325) (ABIN7455024)

抗原

See all Presenilin 2 (PSEN2) 抗体
Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

适用

  • 59
  • 45
  • 34
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 52
  • 4
  • 3
  • 2
  • 2

克隆类型

  • 58
  • 5
多克隆

标记

  • 39
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Presenilin 2 antibody is un-conjugated

应用范围

  • 52
  • 21
  • 18
  • 13
  • 11
  • 10
  • 3
  • 3
  • 3
  • 3
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 275-325

    原理

    Rabbit anti-Presenilin-2 Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Bovine,Pig,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 275 and 325

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

    别名

    Presenilin-2

    背景

    Background: Presenilin-2 is a probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Presenilin-2 requires the other members of the gamma-secretase complex to have a protease activity. It may play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may function in the cytoplasmic partitioning of proteins [taken from the Universal Protein Resource (UniProt) P49810].

    基因ID

    5664

    NCBI登录号

    NP_000438

    UniProt

    P49810

    途径

    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
You are here:
Chat with us!