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SQSTM1 抗体 (AA 325-375)

The 兔 多克隆 anti-SQSTM1 antibody (ABIN7454876) specifically detects SQSTM1 in WB, IP 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7454876
发货至: 中国
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Quick Overview for SQSTM1 抗体 (AA 325-375) (ABIN7454876)

抗原

See all SQSTM1 抗体
SQSTM1 (Sequestosome 1 (SQSTM1))

适用

  • 156
  • 66
  • 65
  • 18
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 128
  • 30
  • 1
  • 1

克隆类型

  • 105
  • 55
多克隆

标记

  • 80
  • 11
  • 9
  • 5
  • 5
  • 5
  • 5
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  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SQSTM1 antibody is un-conjugated

应用范围

  • 120
  • 64
  • 62
  • 52
  • 43
  • 30
  • 28
  • 20
  • 14
  • 14
  • 13
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 16
    • 15
    • 11
    • 11
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-375

    原理

    Rabbit anti-Sequestosome-1 Antibody, Affinity Purified

    预测反应

    Rat,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 325 and 375

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SQSTM1 (Sequestosome 1 (SQSTM1))

    别名

    Sequestosome-1

    背景

    Background: Sequestosome-1 is an adapter protein that binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. Sequestosome-1 may play a role in titin/TTN downstream signaling in muscle cells, and may regulate signaling cascades through ubiquitination. Sequestosome-1 may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels [taken from the Universal Protein Resource (UniProt) Q13501].

    基因ID

    8878

    NCBI登录号

    NP_003891

    UniProt

    Q13501

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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