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BRAF 抗体 (AA 25-75)

This anti-BRAF antibody is a 兔 多克隆 antibody detecting BRAF in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454774
发货至: 中国

Quick Overview for BRAF 抗体 (AA 25-75) (ABIN7454774)

抗原

See all BRAF 抗体
BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

适用

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宿主

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克隆类型

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多克隆

标记

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This BRAF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 25-75

    原理

    Rabbit anti-BRAF Antibody, Affinity Purified

    预测反应

    Mouse

    纯化方法

    Affinity Purified

    免疫原

    between AA 25 and 75

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

    别名

    BRAF

    背景

    Background: B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is a member of the raf/mil family of serine/threonine kinases. BRAF is involved in transducing mitogenic signals via the MAP kinase/ERKs signaling pathway. Mutations in BRAF are involved in a wide range of cancers such as lung, non-Hodgkin lymphoma, and colorectal cancer. Defects in BRAF are also the cause of cardiofaciocutaneous syndrome (CFC), an autosomal dominant syndrome characterized by facial anomalies, heart defects, and ectodermal abnormalities.

    基因ID

    673

    NCBI登录号

    NP_004324

    UniProt

    P15056

    途径

    MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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