CENPF 抗体 (AA 2350-2400)
Quick Overview for CENPF 抗体 (AA 2350-2400) (ABIN7454765)
抗原
See all CENPF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2350-2400
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原理
- Rabbit anti-CENP-F/Mitosin Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 2350 and 2400
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亚型
- IgG
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anti-Centromere Protein F (CENPF) (C-Term) antibody
CENPF 适用: 人 WB, IHC (p), IF, ICC, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein F (CENPF) (AA 436-637) antibodyCENPF 适用: 人 ELISA, WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein F (CENPF) (C-Term) antibodyCENPF 适用: 人, 小鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein F (CENPF) (AA 551-650) antibodyCENPF 适用: 人 ELISA, WB, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein F (CENPF) (C-Term) antibodyVerified CENPF 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CENPF (Centromere Protein F (CENPF))
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别名
- CENP-F/Mitosin
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背景
- Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.
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基因ID
- 1063
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UniProt
- P49454
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途径
- Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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