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CENPF 抗体 (C-Term)

CENPF 适用: 人, 小鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260754
发货至: 中国
  • 抗原 See all CENPF 抗体
    CENPF (Centromere Protein F (CENPF))
    抗原表位
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 25
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 22
    • 3
    • 1
    克隆类型
    • 23
    • 3
    多克隆
    标记
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CENPF antibody is un-conjugated
    应用范围
    • 11
    • 9
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    特异性
    CENPF Antibody detects endogenous levels of total CENPF.
    预测反应
    Pig
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CENPF, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CENPF Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    CENPF (Centromere Protein F (CENPF))
    别名
    CENPF (CENPF 产品)
    别名
    LOC100222985 antibody, 6530404A22Rik antibody, AI325968 antibody, CENF antibody, Lek1 antibody, PRO1779 antibody, mitosin antibody, im:7140452 antibody, im:7144238 antibody, im:7154719 antibody, im:7156761 antibody, si:ch211-152h14.2 antibody, hcp-1 antibody, CMF1 antibody, centromere protein F antibody, CENPF antibody, Cenpf antibody, cenpf antibody
    背景

    Description: Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia.

    Gene: CENPF

    分子量
    367 kDa
    基因ID
    1063
    UniProt
    P49454
    途径
    Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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