PSMC1 抗体 (AA 50-100)
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- 抗原 See all PSMC1 抗体
- PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
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抗原表位
- AA 50-100
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit anti-PSMC1 Antibody, Affinity Purified
- 预测反应
- Rat,D. melanogaster,Chicken
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 50 and 100
- 亚型
- IgG
- Top Product
- Discover our top product PSMC1 Primary Antibody
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anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) antibody
PSMC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 408-436), (C-Term) antibodyPSMC1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB44417 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 1-440) antibodyPSMC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 269-318) antibodyPSMC1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 小鸡, Cow, 豚鼠, 马, 非洲爪蟾, 兔, Pig, 猴, Bat, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 71-120) antibodyPSMC1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 小鸡, Cow, 豚鼠, 马, 非洲爪蟾, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 77-440) antibodyPSMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IP: Not recommended
WB: 1:1,000 - 1:5,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
- 别名
- PSMC1 (PSMC1 产品)
- 别名
- AI325227 antibody, P26s4 antibody, S4 antibody, P26S4 antibody, p56 antibody, s4 antibody, protease (prosome, macropain) 26S subunit, ATPase 1 antibody, proteasome 26S subunit, ATPase 1 antibody, Psmc1 antibody, PSMC1 antibody
- 背景
- Background: Proteasome (prosome, macropain) 26S subunit, ATPase1 (PSMC1) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMC1 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. PSMC1 also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, PSMC1 interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder [taken from NCBI Entrez Gene (Gene ID: 5700)].
- 基因ID
- 5700
- NCBI登录号
- NP_002793
- UniProt
- P62191
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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