-
- 抗原 See all PSMC1 抗体
- PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
-
抗原表位
- AA 77-440
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PSMC1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- PSMC1 Rabbit pAb
- 序列
- EFIRNQEQMK PLEEKQEEER SKVDDLRGTP MSVGTLEEII DDNHAIVSTS VGSEHYVSIL SFVDKDLLEP GCSVLLNHKV HAVIGVLMDD TDPLVTVMKV EKAPQETYAD IGGLDNQIQE IKESVELPLT HPEYYEEMGI KPPKGVILYG PPGTGKTLLA KAVANQTSAT FLRVVGSELI QKYLGDGPKL VRELFRVAEE HAPSIVFIDE IDAIGTKRYD SNSGGEREIQ RTMLELLNQL DGFDSRGDVK VIMATNRIET LDPALIRPGR IDRKIEFPLP DEKTKKRIFQ IHTSRMTLAD DVTLDDLIMA KDDLSGADIK AICTEAGLMA LRERRMKVTN EDFKKSKENV LYKKQEGTPE GLYL
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 77-440 of human PSMC1 (NP_002793.2).
- 亚型
- IgG
- Top Product
- Discover our top product PSMC1 Primary Antibody
-
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) antibody
PSMC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 408-436), (C-Term) antibodyPSMC1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB44417 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 1-440) antibodyPSMC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 269-318) antibodyPSMC1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 小鸡, Cow, 豚鼠, 马, 非洲爪蟾, 兔, Pig, 猴, Bat, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1) (AA 71-120) antibodyPSMC1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 小鸡, Cow, 豚鼠, 马, 非洲爪蟾, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
- 别名
- PSMC1 (PSMC1 产品)
- 别名
- AI325227 antibody, P26s4 antibody, S4 antibody, P26S4 antibody, p56 antibody, s4 antibody, protease (prosome, macropain) 26S subunit, ATPase 1 antibody, proteasome 26S subunit, ATPase 1 antibody, Psmc1 antibody, PSMC1 antibody
- 背景
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder.,PSMC1,P26S4,S4,p56,ATPase 1,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,PSMC1
- 分子量
- 41kDa/49kDa
- 基因ID
- 5700
- UniProt
- P62191
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
-
You are here:
