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MIB2 抗体 (AA 925-975)

MIB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452954
发货至: 中国
  • 抗原 See all MIB2 抗体
    MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 925-975
    适用
    • 17
    • 11
    • 9
    宿主
    • 19
    • 2
    克隆类型
    • 19
    • 2
    多克隆
    标记
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MIB2 antibody is un-conjugated
    应用范围
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit anti-MIB2/Skeletrophin Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 925 and 975
    亚型
    IgG
    Top Product
    Discover our top product MIB2 Primary Antibody
  • 应用备注

    IP: Not recommended

    WB: 1:1,000 - 1:5,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
    别名
    MIB2/Skeletrophin (MIB2 产品)
    别名
    ZZANK1 antibody, ZZZ5 antibody, 2210008I11Rik antibody, Zzank1 antibody, skd antibody, mib2 antibody, mindbomb E3 ubiquitin protein ligase 2 antibody, mindbomb E3 ubiquitin protein ligase 2 S homeolog antibody, MIB2 antibody, Mib2 antibody, mib2 antibody, mib2.S antibody
    背景
    Background: MIB2/Skeletrophin is an actin-binding protein that bears two MIB/HERC2 domains, a ZZ-type zinc-finger domain, nine ankyrin repeats, and two RING-finger domains. The C-terminal RING domain has been found to have E3 ubiquitin ligase activity that mediates ubiquitination of the intracellular regions of the Notch receptor and its ligands to regulate Notch signaling. MIB2/Skeletrophin appears to be important to muscle development and may function as a suppressor of melanoma invasion.
    基因ID
    142678
    NCBI登录号
    NP_543151
    UniProt
    Q96AX9
    途径
    Notch Signaling
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