MIB2 抗体 (AA 925-975)
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- 抗原 See all MIB2 抗体
- MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
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抗原表位
- AA 925-975
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MIB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit anti-MIB2/Skeletrophin Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 925 and 975
- 亚型
- IgG
- Top Product
- Discover our top product MIB2 Primary Antibody
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- 应用备注
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IP: Not recommended
WB: 1:1,000 - 1:5,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
- 别名
- MIB2/Skeletrophin (MIB2 产品)
- 别名
- ZZANK1 antibody, ZZZ5 antibody, 2210008I11Rik antibody, Zzank1 antibody, skd antibody, mib2 antibody, mindbomb E3 ubiquitin protein ligase 2 antibody, mindbomb E3 ubiquitin protein ligase 2 S homeolog antibody, MIB2 antibody, Mib2 antibody, mib2 antibody, mib2.S antibody
- 背景
- Background: MIB2/Skeletrophin is an actin-binding protein that bears two MIB/HERC2 domains, a ZZ-type zinc-finger domain, nine ankyrin repeats, and two RING-finger domains. The C-terminal RING domain has been found to have E3 ubiquitin ligase activity that mediates ubiquitination of the intracellular regions of the Notch receptor and its ligands to regulate Notch signaling. MIB2/Skeletrophin appears to be important to muscle development and may function as a suppressor of melanoma invasion.
- 基因ID
- 142678
- NCBI登录号
- NP_543151
- UniProt
- Q96AX9
- 途径
- Notch Signaling
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