MAP3K1 抗体 (AA 50-100)
Quick Overview for MAP3K1 抗体 (AA 50-100) (ABIN7452708)
抗原
See all MAP3K1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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原理
- Rabbit anti-MEKK1 Antibody, Affinity Purified
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预测反应
- Mouse,Rat
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纯化方法
- Affinity Purified
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免疫原
- between AA 50 and 100
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亚型
- IgG
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应用备注
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IP: 5 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
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别名
- MEKK1
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背景
- Background: MEK (MAPK/ERK kinase) kinase 1 (MEKK1) is encoded by the MAP3K1 (mitogen-activated protein kinase kinase kinase 1) gene. MEKK1 is a component of a protein kinase signal transduction cascade that activates the ERK and JNK kinase pathways by phosphorylation of MEK1 (MAP2K1) and MEK4 (MAP2K4). MEKK1 activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway [taken from the Universal Protein Resource (UniProt) Q13233].
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基因ID
- 4214
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NCBI登录号
- NP_005912
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UniProt
- Q13233
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途径
- MAPK Pathway, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
抗原
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