MAP3K1 抗体 (AA 1077-1176)
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- 抗原 See all MAP3K1 抗体
- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
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抗原表位
- AA 1077-1176
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAP3K1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Partial recombinant MAP3K1 (aa1077-1176) (SKNSMTLDLNSSSKCDDSFGCSSNSSNAVIPSDETVFTP-VEEKCRLDVNTELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAENDDTYKDDVNHNQK)
- 克隆位点
- 2F6
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product MAP3K1 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1307-1509) antibody
MAP3K1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1211-1310) antibodyMAP3K1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1402) antibodyMAP3K1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1400) antibodyMAP3K1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (pThr1400) antibodyMAP3K1 适用: 人 DB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibodyMAP3K1 适用: 人, 小鼠, 大鼠, 兔, Cow, 斑马鱼, 豚鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1211-1310) antibodyMAP3K1 适用: 人 WB, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibodyMAP3K1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (AA 1077-1176) antibodyMAP3K1 适用: 人 WB, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 2F6 unconjugated
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- 应用备注
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Positive Control: A431, HeLa or HL-60 cells. Liver tissue.
Known Application: Western Blot (0.5-1 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris Buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
- 别名
- MAP3K1 (MAP3K1 产品)
- 别名
- MAP3K1 antibody, Mekk1 antibody, MAPKKK1 antibody, MEKK1 antibody, Mekk antibody, ARAKIN antibody, ATMEKK1 antibody, MAPK/ERK kinase kinase 1 antibody, MAPKKK8 antibody, T15F16.5 antibody, T15F16_5 antibody, MEKK antibody, MEKK 1 antibody, SRXY6 antibody, mitogen-activated protein kinase kinase kinase 1 antibody, mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase antibody, MAPK/ERK kinase kinase 1 antibody, MAP3K1 antibody, map3k1 antibody, Map3k1 antibody, MEKK1 antibody
- 背景
- Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (MEK kinase- 5). MEK kinase-1 activates the ERK and c-Jun NH2-terminal kinase (JNK) pathways by phosphorylation of MAP2K1 and MAP2K4, and also activates the central protein kinases of the NFB pathway, CHUK and IKBKB. Additionally, MEK kinase-1 uses an E3 ligase through its PHD domain, a RING-finger-like structure, to target proteins for degradation through ubiquitination.
- 分子量
- 195kDa (intact), 80kDa (cleaved)
- 基因ID
- 4214
- UniProt
- Q13233
- 途径
- MAPK Pathway, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
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