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Retinoblastoma 1 抗体 (AA 550-600)

This anti-Retinoblastoma 1 antibody is a 兔 多克隆 antibody detecting Retinoblastoma 1 in IP. Suitable for 人.
产品编号 ABIN7449625
发货至: 中国

Quick Overview for Retinoblastoma 1 抗体 (AA 550-600) (ABIN7449625)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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宿主

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克隆类型

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  • 57
多克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP)
  • 抗原表位

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    AA 550-600

    原理

    Rabbit anti-Rb1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 550 and 600

    亚型

    IgG
  • 应用备注

    IP: 10 - 15 μg/mg lysate

    WB: Not recommended.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    Rb1

    背景

    Background: Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma [taken from NCBI Entrez Gene (GeneID: 5925)].

    基因ID

    5925

    NCBI登录号

    NP_000312

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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