MCM2 抗体 (pSer41)
Quick Overview for MCM2 抗体 (pSer41) (ABIN7449367)
抗原
See all MCM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer41
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原理
- Rabbit anti-Phospho MCM2 (S41) Antibody, Affinity Purified
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预测反应
- X. laevis,X. tropicalis
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纯化方法
- Affinity Purified
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免疫原
- surrounding serine 41
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亚型
- IgG
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:5,000 - 1:20,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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别名
- MCM2
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背景
- Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.
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基因ID
- 4171
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NCBI登录号
- NP_004517
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UniProt
- P49736
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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