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CHEK2 抗体 (AA 475-525)

This anti-CHEK2 antibody is a 兔 多克隆 antibody detecting CHEK2 in IHC. Suitable for 人.
产品编号 ABIN7448477
发货至: 中国

Quick Overview for CHEK2 抗体 (AA 475-525) (ABIN7448477)

抗原

See all CHEK2 抗体
CHEK2 (Checkpoint Kinase 2 (CHEK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CHEK2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
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    AA 475-525

    原理

    Rabbit anti-Chk2 IHC Antibody, Affinity Purified

    预测反应

    Orangutan,Chimpanzee

    纯化方法

    Affinity Purified

    免疫原

    Between AA 475 and 525

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    500 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CHEK2 (Checkpoint Kinase 2 (CHEK2))

    别名

    Chk2

    背景

    Background: Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are RAD53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, Brca1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, RAD53, HuCds1, and PP1425.

    基因ID

    11200

    NCBI登录号

    NP_009125

    UniProt

    O96017

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle
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