Lamin A/C 抗体
Quick Overview for Lamin A/C 抗体 (ABIN7384462)
抗原
See all Lamin A/C (LMNA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Purified
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亚型
- IgG
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应用备注
- WB 1:1000-1:2000 IHC 1:50-1:100
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限制
- 仅限研究用
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浓度
- 300 μg/mL
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缓冲液
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Lamin A/C (LMNA)
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别名
- Lamin A/C
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背景
- 70 kDa lamin,Cardiomyopathy dilated 1A (autosomal dominant),CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,FPLD2,HGPS,IDC,Lamin A,Lamin A/C,Lamin A/C like 1,Lamin,Lamin C,Lamin-A/C,LDP1,LFP,LGMD1B,Limb girdle muscular dystrophy 1B (autosomal dominant),LMN 1,LMN A,LMN C,LMN1,LMNA,LMNA,LMNC,LMNL1,Prelamin A/C,PRO1,Renal carcinoma antigen NY REN 32,Renal carcinoma antigen NY-REN-32,Renal carcinoma antigen NYREN32,The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
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分子量
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Observed_MW: 74/63 kDa
Calculated_MW: 74 kDa
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基因ID
- 4000
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UniProt
- P02545
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途径
- Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
抗原
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