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Lamin A/C 抗体

This anti-Lamin A/C antibody is a 兔 单克隆 antibody detecting Lamin A/C in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7384462
发货至: 中国

Quick Overview for Lamin A/C 抗体 (ABIN7384462)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠

宿主

  • 104
  • 45
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  • 1

克隆类型

  • 103
  • 49
单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

R07-1I5
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000 IHC 1:50-1:100

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A/C

    背景

    70 kDa lamin,Cardiomyopathy dilated 1A (autosomal dominant),CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,FPLD2,HGPS,IDC,Lamin A,Lamin A/C,Lamin A/C like 1,Lamin,Lamin C,Lamin-A/C,LDP1,LFP,LGMD1B,Limb girdle muscular dystrophy 1B (autosomal dominant),LMN 1,LMN A,LMN C,LMN1,LMNA,LMNA,LMNC,LMNL1,Prelamin A/C,PRO1,Renal carcinoma antigen NY REN 32,Renal carcinoma antigen NY-REN-32,Renal carcinoma antigen NYREN32,The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.

    分子量

    Observed_MW: 74/63 kDa

    Calculated_MW: 74 kDa

    基因ID

    4000

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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