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- 抗原 See all ZCCHC3 products
- ZCCHC3 (Zinc Finger, C3HC-Type Containing 3 (ZCCHC3))
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抗原表位
- AA 215-335
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZCCHC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- ZCCHC3 Rabbit pAb
- 序列
- SFRSAEKLAL FLRVYEEKRE QEDCWENFVV LGRSKSSLKT LFILFRNETV DVEDIVTWLK RHCDVLAVPV KVTDRFGIWT GEYKCEIELR QGEGGVRHLP GAFFLGAERG YSWYKGQPKT C
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 215-335 of human ZCCHC3 (NP_149080.2).
- 亚型
- IgG
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anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) antibody
ZCCHC3 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 181-230) antibodyZCCHC3 适用: 人, 小鼠, Cow, 大鼠, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 1-403) antibodyZCCHC3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (N-Term) antibodyZCCHC3 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 210-238) antibodyZCCHC3 适用: 人 WB 宿主: 兔 Polyclonal RB40474 unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (Middle Region) antibodyZCCHC3 适用: 人, 小鼠, Cow, 大鼠, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) antibodyZCCHC3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ZCCHC3 (Zinc Finger, C3HC-Type Containing 3 (ZCCHC3))
- 别名
- ZCCHC3 (ZCCHC3 产品)
- 别名
- C20orf99 antibody, 2810406K24Rik antibody, zinc finger CCHC-type containing 3 antibody, zinc finger, CCHC domain containing 3 antibody, ZCCHC3 antibody, Zcchc3 antibody
- 背景
- Nucleic acid-binding protein involved in innate immune response to DNA and RNA viruses. Binds DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS. Acts as a co-sensor for recognition of double-stranded DNA (dsDNA by cGAS in the cytoplasm, thereby playing a role in innate immune response to cytosolic dsDNA and DNA virus. Binds dsDNA and probably acts by promoting sensing of dsDNA by CGAS, leading to enhance CGAS oligomerization and activation. Promotes sensing of viral RNA by RIG-I-like receptors proteins DDX58/RIG-I and IFIH1/MDA5 via two mechanisms: binds double-stranded RNA (dsRNA, enhancing the binding of DDX58/RIG-I and IFIH1/MDA5 to dsRNA and promotes 'Lys-63'-linked ubiquitination and subsequent activation of DDX58/RIG-I and IFIH1/MDA5.,ZCCHC3,C20orf99,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,ZCCHC3
- 分子量
- 43kDa
- 基因ID
- 85364
- UniProt
- Q9NUD5
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