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- 抗原 See all ZCCHC3 products
- ZCCHC3 (Zinc Finger, C3HC-Type Containing 3 (ZCCHC3))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZCCHC3 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human ZCCHC3 (NP_149080.2).
- 亚型
- IgG
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anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 215-335) antibody
ZCCHC3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 181-230) antibodyZCCHC3 适用: 人, 小鼠, Cow, 大鼠, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 1-403) antibodyZCCHC3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (N-Term) antibodyZCCHC3 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (AA 210-238) antibodyZCCHC3 适用: 人 WB 宿主: 兔 Polyclonal RB40474 unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) (Middle Region) antibodyZCCHC3 适用: 人, 小鼠, Cow, 大鼠, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, C3HC-Type Containing 3 (ZCCHC3) antibodyZCCHC3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ZCCHC3 (Zinc Finger, C3HC-Type Containing 3 (ZCCHC3))
- 别名
- ZCCHC3 (ZCCHC3 产品)
- 别名
- C20orf99 antibody, 2810406K24Rik antibody, zinc finger CCHC-type containing 3 antibody, zinc finger, CCHC domain containing 3 antibody, ZCCHC3 antibody, Zcchc3 antibody
- 背景
- Nucleic acid-binding protein involved in innate immune response to DNA and RNA viruses (PubMed:30193849, PubMed:30135424). Binds DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS (PubMed:30193849, PubMed:30135424). Acts as a co-sensor for recognition of double-stranded DNA (dsDNA) by cGAS in the cytoplasm, thereby playing a role in innate immune response to cytosolic dsDNA and DNA virus (PubMed:30135424). Binds dsDNA and probably acts by promoting sensing of dsDNA by CGAS, leading to enhance CGAS oligomerization and activation (PubMed:30135424). Promotes sensing of viral RNA by RIG-I-like receptors proteins DDX58/RIG-I and IFIH1/MDA5 via two mechanisms: binds double-stranded RNA (dsRNA), enhancing the binding of DDX58/RIG-I and IFIH1/MDA5 to dsRNA and promotes 'Lys-63'-linked ubiquitination and subsequent activation of DDX58/RIG-I and IFIH1/MDA5.
- 基因ID
- 85364
- UniProt
- Q9NUD5
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