p53 抗体 (pSer9)
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北京 101111
Quick Overview for p53 抗体 (pSer9) (ABIN7271093)
抗原
See all p53 (TP53) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer9
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原理
- Phospho-p53-S9 Rabbit mAb
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交叉反应
- 人, 小鼠
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding S9 of human p53
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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别名
- TP53
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背景
- This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016],BCC7, LFS1, P53, TRP53,AMPK Signaling Pathway,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,G1/S Checkpoint,G2/M DNA Damage Checkpoint,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Neurodegenerative Diseases,Neuroscience,PI3K-Akt Signaling Pathway,Protein phosphorylation,Signal Transduction,Transcription Factors,Tumor suppressors,Tumor suppressors_p53 pathway,Warburg Effect,TP53
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分子量
- 53kDa
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基因ID
- 7157
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UniProt
- P04637
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途径
- p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
抗原
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