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SMAD7 抗体 (AA 1-100)

SMAD7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7270356
发货至: 中国
  • 抗原 See all SMAD7 抗体
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    抗原表位
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 45
    • 26
    • 24
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 38
    • 7
    克隆类型
    • 39
    • 6
    多克隆
    标记
    • 28
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD7 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 14
    • 14
    • 9
    • 8
    • 7
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Smad7 Rabbit pAb
    序列
    MFRTKRSALV RRLWRSRAPG GEDEEEGAGG GGGGGELRGE GATDSRAHGA GGGGPGRAGC CLGKAVRGAK GHHHPHPPAA GAGAAGGAEA DLKALTHSVL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad7 (NP_005895.1).
    亚型
    IgG
    Top Product
    Discover our top product SMAD7 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    别名
    SMAD7 (SMAD7 产品)
    别名
    CRCS3 antibody, MADH7 antibody, MADH8 antibody, Smad7a antibody, Madh7 antibody, Smad10 antibody, madh7 antibody, xsmad7 antibody, wu:fj60c10 antibody, SMAD family member 7 antibody, SMAD family member 7 L homeolog antibody, SMAD7 antibody, Smad7 antibody, smad7.L antibody, smad7 antibody
    背景
    The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.,SMAD7,CRCS3,MADH7,MADH8,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,SMADs,SMAD7
    分子量
    23kDa/46kDa
    基因ID
    4092
    UniProt
    O15105
    途径
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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