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SMAD7 抗体

SMAD7 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256046
发货至: 中国
  • 抗原 See all SMAD7 抗体
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    适用
    • 45
    • 25
    • 23
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 38
    • 7
    克隆类型
    • 39
    • 6
    多克隆
    标记
    • 28
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD7 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 14
    • 14
    • 9
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human SMAD7 (NP_005895.1).
    亚型
    IgG
    Top Product
    Discover our top product SMAD7 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    别名
    SMAD7 (SMAD7 产品)
    别名
    CRCS3 antibody, MADH7 antibody, MADH8 antibody, Smad7a antibody, Madh7 antibody, Smad10 antibody, madh7 antibody, xsmad7 antibody, wu:fj60c10 antibody, SMAD family member 7 antibody, SMAD family member 7 L homeolog antibody, SMAD7 antibody, Smad7 antibody, smad7.L antibody, smad7 antibody
    背景
    The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 46 kDa

    Calculated_MW: 23 kDa/46 kDa

    基因ID
    4092
    UniProt
    O15105
    途径
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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