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SQSTM1 抗体

This anti-SQSTM1 antibody is a 兔 单克隆 antibody detecting SQSTM1 in WB, IHC, IF 和 IP. Suitable for 人.
产品编号 ABIN7270205
发货至: 中国

Quick Overview for SQSTM1 抗体 (ABIN7270205)

抗原

See all SQSTM1 抗体
SQSTM1 (Sequestosome 1 (SQSTM1))

适用

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宿主

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克隆类型

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单克隆

标记

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This SQSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

质量等级

KO Validated
  • 原理

    [KO Validated] SQSTM1/p62 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human SQSTM1/p62.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SQSTM1 (Sequestosome 1 (SQSTM1))

    别名

    SQSTM1

    背景

    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.,SQSTM1,A170,DMRV,FTDALS3,NADGP,OSIL,PDB3,ZIP3,p60,p62,p62B,Apoptosis,Autophagy,Autophagy_Mitochondrial Control of Autophagy,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Mitochondrial metabolism,Signal Transduction,SQSTM1

    分子量

    62kDa

    基因ID

    8878

    UniProt

    Q13501

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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