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Retinoblastoma 1 抗体 (pSer780)

This anti-Retinoblastoma 1 antibody is a 兔 单克隆 antibody detecting Retinoblastoma 1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7269936
发货至: 中国

Quick Overview for Retinoblastoma 1 抗体 (pSer780) (ABIN7269936)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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宿主

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克隆类型

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单克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pSer780

    原理

    Phospho-RB-S780 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho synthetic peptide corresponding to residues surrounding S780 of human RB.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    RB1

    背景

    The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Protein phosphorylation,Transcription Factors,Tumor suppressors,RB1

    分子量

    106kDa

    基因ID

    5925

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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