Phospholipase C gamma 2 抗体 (pTyr759)
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- 抗原 See all Phospholipase C gamma 2 (PLCG2) 抗体
- Phospholipase C gamma 2 (PLCG2)
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抗原表位
- pTyr759
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Phospholipase C gamma 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Phospho-PLC gamma 2 (PLCG2)-Y759 Rabbit pAb
- 序列
- RMYVD
- 交叉反应
- 人
- 产品特性
- Phosphorylated Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic phosphorylated peptide around Y759 of human PLC gamma 2 (PLCG2) (NP_002652.2).
- 亚型
- IgG
- Top Product
- Discover our top product PLCG2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Phospholipase C gamma 2 (PLCG2)
- 别名
- PLCG2 (PLCG2 产品)
- 背景
- The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.,PLCG2,APLAID,FCAS3,PLC-IV,PLC-gamma-2,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,Protein phosphorylation,PLCG2
- 分子量
- 147kDa
- 基因ID
- 5336
- UniProt
- P16885
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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