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Phospholipase C gamma 2 抗体 (pTyr753)

PLCG2 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A8B6 unconjugated
产品编号 ABIN5611155
发货至: 中国
  • 抗原 See all Phospholipase C gamma 2 (PLCG2) 抗体
    Phospholipase C gamma 2 (PLCG2)
    抗原表位
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    pTyr753
    适用
    • 130
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    宿主
    • 125
    • 5
    小鼠
    克隆类型
    • 121
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    单克隆
    标记
    • 59
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    This Phospholipase C gamma 2 antibody is un-conjugated
    应用范围
    • 95
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    免疫原
    Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)).
    克隆位点
    3A8B6
    亚型
    IgG2b
    Top Product
    Discover our top product PLCG2 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    Phospholipase C gamma 2 (PLCG2)
    别名
    PLCG2 (PLCG2 产品)
    别名
    PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
    背景

    Description: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

    Aliases: FCAS3, APLAID, PLC-IV, PLC-gamma-2

    分子量
    148 kDa
    基因ID
    5336
    HGNC
    5336
    途径
    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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