Phospholipase C gamma 2 产品
(Phospholipase C gamma 2 (PLCG2))
Categories
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].
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Featured Phospholipase C gamma 2 Categories
Phospholipase C gamma 2 抗体
High quality antibodies with extensive validation data.
Phospholipase C gamma 2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Phospholipase C gamma 2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Phospholipase C gamma 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN3023145
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (4)
Cat. No.
ABIN518951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN948268
Quantity
100 μL
Datasheet
Datasheet
Recommended Phospholipase C gamma 2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969306
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958573
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380130
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended Phospholipase C gamma 2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094665
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3136487
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397702
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Phospholipase C gamma 2 Products
: "PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras." in: Science signaling, Vol. 6, Issue 304, pp. ra105, (2013) (PubMed).: "Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells." in: Molecular immunology, Vol. 46, Issue 15, pp. 3029-36, (2009) (PubMed).
: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, (2004) (PubMed).
: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, (2004) (PubMed).
: "Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker." in: The Journal of biological chemistry, Vol. 279, Issue 36, pp. 37651-61, (2004) (PubMed).
: "Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 38595-601, (2001) (PubMed).
: "Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C." in: The Journal of biological chemistry, Vol. 275, Issue 39, pp. 30220-5, (2000) (PubMed).
: "Complete cDNA encoding a putative phospholipase C from transformed human lymphocytes." in: FEBS letters, Vol. 242, Issue 1, pp. 31-5, (1989) (PubMed).
Synonyms and alternative names related to Phospholipase C gamma 2
phospholipase C, gamma 2 (Plcg2), phospholipase C gamma 2 (PLCG2), phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2), phospholipase C gamma 2 (Plcg2), APLAID, FCAS3, Plcg-2, PLCgamma2Protein level used designations for Phospholipase C gamma 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2
- PLC-gamma-2
- phosphoinositide phospholipase C-gamma-2
- phospholipase C-gamma-2
- PLC-IV
- phosphoinositide phospholipase C
- phospholipase C-IV
- phosphatidylinositol-specific phospholipase C
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