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PILRA 抗体

PILRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269157
发货至: 中国
  • 抗原 See all PILRA 抗体
    PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
    适用
    • 11
    • 1
    宿主
    • 7
    • 3
    • 1
    • 1
    克隆类型
    • 9
    • 3
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This PILRA antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 1
    • 1
    Western Blotting (WB)
    原理
    PILRA Rabbit pAb
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PILRA.
    亚型
    IgG
    Top Product
    Discover our top product PILRA Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
    别名
    PILRA (PILRA 产品)
    别名
    PILRA antibody, FDF03 antibody, AV021745 antibody, RGD1562847 antibody, paired immunoglobin like type 2 receptor alpha antibody, paired immunoglobulin-like type 2 receptor alpha antibody, paired immunoglobin-like type 2 receptor alpha antibody, PILRA antibody, LOC489841 antibody, Pilra antibody
    背景
    Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.,PILRA,FDF03,PILRA
    分子量
    34kDa
    基因ID
    29992
    UniProt
    Q9UKJ1
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