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- 抗原 See all PILRA 抗体
- PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PILRA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IPFSFYYPWE LATAPDVRIS WRRGHFHRQS FYSTRPPSIH KDYVNRLFLN
- 特异性
- 100 % homologous to all four isoforms of human PILRA.
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PILRA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PILRA
- Top Product
- Discover our top product PILRA Primary Antibody
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anti-Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 1-226) antibody
PILRA 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 22-226) antibodyPILRA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 51-100) antibodyPILRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) antibodyPILRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 175 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
- 别名
- PILRA (PILRA 产品)
- 别名
- PILRA antibody, FDF03 antibody, AV021745 antibody, RGD1562847 antibody, paired immunoglobin like type 2 receptor alpha antibody, paired immunoglobulin-like type 2 receptor alpha antibody, paired immunoglobin-like type 2 receptor alpha antibody, PILRA antibody, LOC489841 antibody, Pilra antibody
- 背景
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Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.
Alias Symbols: FDF03
Protein Interaction Partner: DNPH1, SORBS1, PTPN6, PTPN11, FCAR,
Protein Size: 175 - 分子量
- 18 kDa
- 基因ID
- 29992
- NCBI登录号
- NM_178273, NP_840057
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