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NCF4 抗体 (pThr154)

NCF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7268901
发货至: 中国
  • 抗原 See all NCF4 抗体
    NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
    抗原表位
    • 18
    • 15
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr154
    适用
    • 79
    • 25
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 74
    • 5
    • 1
    克隆类型
    • 77
    • 3
    多克隆
    标记
    • 35
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This NCF4 antibody is un-conjugated
    应用范围
    • 39
    • 26
    • 26
    • 20
    • 16
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    原理
    Phospho-NCF4/p40-phox-T154 Rabbit pAb
    交叉反应
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic phosphorylated peptide around T154 of human NCF4.
    亚型
    IgG
    Top Product
    Discover our top product NCF4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
    别名
    NCF4 (NCF4 产品)
    别名
    p40phox antibody, AI451400 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody, neutrophil cytosolic factor 4 antibody, ncf4 antibody, Ncf4 antibody, NCF4 antibody
    背景
    The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.,NCF4,CGD3,NCF,P40PHOX,SH3PXD4,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,NCF4
    分子量
    39kDa
    基因ID
    4689
    UniProt
    Q15080
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