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NCF4 抗体

NCF4 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268900
发货至: 中国
  • 抗原 See all NCF4 抗体
    NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
    适用
    • 80
    • 25
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 75
    • 5
    • 1
    克隆类型
    • 78
    • 3
    单克隆
    标记
    • 36
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This NCF4 antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 26
    • 20
    • 15
    • 12
    • 7
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    原理
    NCF4/p40-phox Rabbit mAb
    交叉反应
    人, 小鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human NCF4/p40-phox.
    亚型
    IgG
    Top Product
    Discover our top product NCF4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
    别名
    NCF4 (NCF4 产品)
    别名
    p40phox antibody, AI451400 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody, neutrophil cytosolic factor 4 antibody, ncf4 antibody, Ncf4 antibody, NCF4 antibody
    背景
    The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.,NCF4, CGD3, NCF, P40PHOX, SH3PXD4, neutrophil cytosol factor 4,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,NCF4
    分子量
    39kDa
    基因ID
    4689
    UniProt
    Q15080
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