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- 抗原 See all GPX4 抗体
- GPX4 (Glutathione Peroxidase 4 (GPX4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This GPX4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- [KO Validated] GPX4 Rabbit mAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 质量等级
- KO Validated
- 免疫原
- A synthesized peptide derived from human GPX4
- 亚型
- IgG
- Top Product
- Discover our top product GPX4 Primary Antibody
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anti-Glutathione Peroxidase 4 (GPX4) (AA 30-197) antibody
GPX4 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibodyGPX4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibodyVerified GPX4 适用: 人 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) antibodyGPX4 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) antibodyGPX4 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF, FACS, Coat, StM 宿主: 小鼠 Monoclonal LHM 2 unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 72-121) antibodyGPX4 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 猴, 山羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 81-93) antibodyGPX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- GPX4 (Glutathione Peroxidase 4 (GPX4))
- 别名
- GPX4 (GPX4 产品)
- 别名
- GPx-4 antibody, GSHPx-4 antibody, MCSP antibody, PHGPx antibody, snGPx antibody, snPHGPx antibody, Phgpx antibody, gpx-4 antibody, snGpx antibody, cb563 antibody, cb691 antibody, PHGPxa antibody, sb:cb563 antibody, zgc:92253 antibody, wu:fb82e03 antibody, 1700027O09Rik antibody, mtPHGPx antibody, ATGPX4 antibody, F11L15.5 antibody, glutathione peroxidase 4 antibody, GP-GPx4 antibody, glutathione peroxidase 4 antibody, glutathione peroxidase 4a antibody, GPX4 antibody, Gpx4 antibody, gpx4a antibody
- 背景
- The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016],GPx-4, GSHPx-4, MCSP, PHGPx, SMDS, snGPx, snPHGPx,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,GPX4
- 分子量
- 19kDa/22kDa
- 基因ID
- 2879
- UniProt
- P36969
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