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GPX4 抗体

GPX4 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF, FACS, Coat, StM 宿主: 小鼠 Monoclonal LHM 2 unconjugated
产品编号 ABIN6939550
发货至: 中国
  • 抗原 See all GPX4 抗体
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    适用
    • 46
    • 35
    • 30
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 47
    • 3
    • 1
    小鼠
    克隆类型
    • 38
    • 13
    单克隆
    标记
    • 25
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPX4 antibody is un-conjugated
    应用范围
    • 35
    • 17
    • 17
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    A 375P cells crude extract
    克隆位点
    LHM 2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GPX4 Primary Antibody
  • 应用备注

    Positive Control: MCF7 or HepG2 cells. Human brain or malignant melanoma.

    Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    别名
    GPX4 (GPX4 产品)
    别名
    GPx-4 antibody, GSHPx-4 antibody, MCSP antibody, PHGPx antibody, snGPx antibody, snPHGPx antibody, Phgpx antibody, gpx-4 antibody, snGpx antibody, cb563 antibody, cb691 antibody, PHGPxa antibody, sb:cb563 antibody, zgc:92253 antibody, wu:fb82e03 antibody, 1700027O09Rik antibody, mtPHGPx antibody, ATGPX4 antibody, F11L15.5 antibody, glutathione peroxidase 4 antibody, GP-GPx4 antibody, glutathione peroxidase 4 antibody, glutathione peroxidase 4a antibody, GPX4 antibody, Gpx4 antibody, gpx4a antibody
    背景
    Glutathione Peroxidase 4 (GPX4) stabilizes cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. NG2 may facilitate primary melanoma progression by enhancing the activation of key signaling pathways important for tumor invasion and growth. Threonine 2256 phosphorylation of rat NG2 (threonine 2252 phosphorylation of human NG2) leads to redistribution of NG2 on the surface of astrocytomas, polarization of the cell and a significant increase in cell motility. NG2 acts as a co-receptor for spreading and focal contact formation in association with 1 integrin in malignant melanoma cells. NG2 is present on blood vessels throughout the rat embryo. Microvessels within the rat CNS express NG2 on endothelial cells, and outside the CNS, NG2 is present on smooth muscle cells. NG2 is a novel marker for epidermal stem cells that contributes to their patterned distribution by promoting stem cell clustering.
    分子量
    21kDa
    基因ID
    2879
    UniProt
    P36969
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