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C4A 抗体 (AA 1200-1446)

C4a 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7266482
发货至: 中国
  • 抗原 See all C4A (C4a) 抗体
    C4A (C4a) (Complement Fragment C4a (C4a))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1200-1446
    适用
    • 19
    • 6
    • 2
    • 2
    宿主
    • 17
    • 6
    • 1
    克隆类型
    • 16
    • 8
    多克隆
    标记
    • 17
    • 3
    • 2
    • 1
    • 1
    This C4A antibody is un-conjugated
    应用范围
    • 14
    • 14
    • 11
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Complement C4A Rabbit pAb
    序列
    LTLTKAPVDL LGVAHNNLMA MAQETGDNLY WGSVTGSQSN AVSPTPAPRN PSDPMPQAPA LWIETTAYAL LHLLLHEGKA EMADQASAWL TRQGSFQGGF RSTQDTVIAL DALSAYWIAS HTTEERGLNV TLSSTGRNGF KSHALQLNNR QIRGLEEELQ FSLGSKINVK VGGNSKGTLK VLRTYNVLDM KNTTCQDLQI EVTVKGHVEY TMEANEDYED YEYDELPAKD DPDAPLQPVT PLQLFEG
    交叉反应
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1446 of human Complement C4A (NP_009224.2).
    亚型
    IgG
    Top Product
    Discover our top product C4a Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    C4A (C4a) (Complement Fragment C4a (C4a))
    别名
    C4A (C4a 产品)
    别名
    C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CO4 antibody, CPAMD2 antibody, RG antibody, Slp antibody, C4-1 antibody, C4b antibody, complement C4A (Rodgers blood group) antibody, complement component 4A (Rodgers blood group) antibody, C4A antibody, C4a antibody
    背景
    This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene.,C4A,C4,C4A2,C4A3,C4A4,C4A6,C4AD,C4S,CO4,CPAMD2,RG,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C4A
    分子量
    187kDa/192kDa
    基因ID
    720
    UniProt
    P0C0L4
    途径
    Complement System
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