This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
BAD
(BCL2-Associated Agonist of Cell Death (BAD))
别名
BAD
背景
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008],BBC2, BCL2L8,Apoptosis,Apoptosis_Bcl 2 family,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,ErbB-HER Signaling Pathway,Immunology & Inflammation,Insulin Receptor Signaling Pathway,Invasion and Metastasis,MAPK-Erk Signaling Pathway,Neurodegenerative Diseases,Neuroscience,PI3K-Akt Signaling Pathway,Protein phosphorylation,Signal Transduction,BAD