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BAD 抗体 (AA 53-81)

BAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06939 unconjugated
产品编号 ABIN388109
发货至: 中国
  • 抗原 See all BAD 抗体
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    抗原表位
    • 34
    • 34
    • 27
    • 27
    • 26
    • 24
    • 24
    • 23
    • 15
    • 11
    • 11
    • 8
    • 8
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    • 8
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    • 2
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    • 2
    • 1
    • 1
    • 1
    AA 53-81
    适用
    • 383
    • 223
    • 146
    • 17
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 459
    • 15
    • 1
    克隆类型
    • 441
    • 34
    多克隆
    标记
    • 180
    • 43
    • 38
    • 38
    • 36
    • 33
    • 11
    • 11
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    • 6
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    • 6
    • 6
    • 6
    • 2
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    • 1
    This BAD antibody is un-conjugated
    应用范围
    • 258
    • 256
    • 163
    • 104
    • 81
    • 80
    • 56
    • 55
    • 22
    • 19
    • 13
    • 10
    • 9
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Bad antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human Bad.
    克隆位点
    RB06939
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Lu, Zhang, Tan, Luo, Zhao, Ma, Liang, Tan: "GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia." in: International journal of molecular medicine, Vol. 38, Issue 1, pp. 105-12, (2017) (PubMed).

    Hu, Kuo, Senadi, Chang, Wang: "Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells." in: Anticancer research, Vol. 37, Issue 10, pp. 5499-5505, (2017) (PubMed).

    Shan, Yan, Diao, Lin, Wang, Zhang, Zhang, Wei: "Involvement of caspases and their upstream regulators in myocardial apoptosis in a rat model of selenium deficiency-induced dilated cardiomyopathy." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 31, pp. 85-91, (2015) (PubMed).

  • 抗原
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    别名
    Bad (BAD 产品)
    别名
    bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
    背景
    Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
    分子量
    18392
    基因ID
    572
    NCBI登录号
    NP_004313, NP_116784
    UniProt
    Q92934
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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