BRAF 抗体 (pThr401)
Our Local Distributor
北京 101111
Quick Overview for BRAF 抗体 (pThr401) (ABIN7265819)
抗原
See all BRAF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr401
-
原理
- Phospho-B-Raf-T401 Rabbit mAb
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Phosphorylated Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A phospho specific peptide corresponding to residues surrounding T401 of human B Raf
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
-
别名
- BRAF
-
背景
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008],B-RAF1, B-raf, BRAF1, NS7, RAFB1,Apoptosis,Apoptosis_Inhibition of Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Kinase_Tyrosine kinases,MAPK-Erk Signaling Pathway,Neuroscience,Protein phosphorylation,Signal Transduction,T Cell Receptor Signaling Pathway,BRAF
-
分子量
- 85kDa
-
基因ID
- 673
-
UniProt
- P15056
-
途径
- MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
抗原
-