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BRAF 抗体 (pThr401)

This anti-BRAF antibody is a 兔 单克隆 antibody detecting BRAF in WB. Suitable for 人.
产品编号 ABIN7265819
发货至: 中国

Quick Overview for BRAF 抗体 (pThr401) (ABIN7265819)

抗原

See all BRAF 抗体
BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

适用

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宿主

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克隆类型

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单克隆

标记

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This BRAF antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pThr401

    原理

    Phospho-B-Raf-T401 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding T401 of human B Raf

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

    别名

    BRAF

    背景

    This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008],B-RAF1, B-raf, BRAF1, NS7, RAFB1,Apoptosis,Apoptosis_Inhibition of Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Kinase_Tyrosine kinases,MAPK-Erk Signaling Pathway,Neuroscience,Protein phosphorylation,Signal Transduction,T Cell Receptor Signaling Pathway,BRAF

    分子量

    85kDa

    基因ID

    673

    UniProt

    P15056

    途径

    MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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