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- 抗原 See all ALK 抗体
- ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
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抗原表位
- AA 19-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- ALK Rabbit pAb
- 序列
- VGSGMGTGQR AGSPAAGPPL QPREPLSYSR LQRKSLAVDF VVPSLFRVYA RDLLLPPSSS ELKAGRPEAR GSLALDCAPL LRLLGPAPGV SWTAGSPAPA EARTLSRVLK GGSVRKLRRA KQLVLELGEE AILEGCVGPP GEAAVGLLQF NLSELFSWWI RQGEGRLRIR LMPEKKASEV GREGRLSAAI RASQPRLLFQ IFGTGHSSLE SPTNMPSPSP DYFTWNLTWI MKDSFPFLSH RSRYGLECSF DFPCELEYSP PLHDLRNQSW SWRRIPSEEA SQ
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 19-300 of human ALK (NP_004295.2).
- 亚型
- IgG
- Top Product
- Discover our top product ALK Primary Antibody
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anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1348-1611) antibody
ALK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1402-1604) antibodyALK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 636-666) antibodyALK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15425 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 14-43), (N-Term) antibodyALK 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB1511-1512 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1591-1620), (C-Term) antibodyALK 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB1513-1514 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 636-666) antibodyALK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1466-1500), (C-Term) antibodyALK 适用: 人 WB 宿主: 兔 Polyclonal RB50500 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1517-1550) antibodyALK 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50288 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1517-1550) antibodyALK 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
- 别名
- ALK (ALK 产品)
- 别名
- Tcrz antibody, CD246 antibody, NBLST3 antibody, ALK antibody, anaplastic lymphoma kinase antibody, anaplastic lymphoma receptor tyrosine kinase antibody, ALK receptor tyrosine kinase antibody, Alk antibody, ALK antibody
- 背景
- This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).,ALK,CD246,NBLST3,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Neuron marker,ALK
- 分子量
- 176kDa
- 基因ID
- 238
- UniProt
- Q9UM73
- 途径
- RTK signaling
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