SGK1 抗体
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北京 101111
Quick Overview for SGK1 抗体 (ABIN7212186)
抗原
See all SGK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SGK1 Mouse Monoclonal Antibody (4D12)
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特异性
- SGK1 protein detects endogenous levels of SGK1.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
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免疫原
- Synthetic Peptide of SGK1 at AA range of 350-430
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亚型
- IgG1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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别名
- SGK1
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背景
- Mouse Anti-SGK1 Mouse Monoclonal Antibody (4D12),SGK1,SGK1 (serum/glucocorticoid regulated kinase 1) encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for SGK1.,SGK1
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分子量
- observerd band 45-60kDa
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基因ID
- 6446
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UniProt
- O00141
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途径
- MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
抗原
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