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SGK1 抗体

This 小鼠 单克隆 anti-SGK1 antibody (Clone 4D12) specifically detects SGK1 in IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7212186
发货至: 中国
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Room 801-803
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Quick Overview for SGK1 抗体 (ABIN7212186)

抗原

See all SGK1 抗体
SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

  • 147
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单克隆

标记

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This SGK1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4D12
  • 原理

    SGK1 Mouse Monoclonal Antibody (4D12)

    特异性

    SGK1 protein detects endogenous levels of SGK1.

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Synthetic Peptide of SGK1 at AA range of 350-430

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

    别名

    SGK1

    背景

    Mouse Anti-SGK1 Mouse Monoclonal Antibody (4D12),SGK1,SGK1 (serum/glucocorticoid regulated kinase 1) encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for SGK1.,SGK1

    分子量

    observerd band 45-60kDa

    基因ID

    6446

    UniProt

    O00141

    途径

    MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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