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Retinoblastoma Binding Protein 8 抗体

This 兔 多克隆 anti-Retinoblastoma Binding Protein 8 antibody specifically detects Retinoblastoma Binding Protein 8 in ELISA 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7223950
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Retinoblastoma Binding Protein 8 抗体 (ABIN7223950)

抗原

See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
Retinoblastoma Binding Protein 8 (RBBP8)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Retinoblastoma Binding Protein 8 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    CtIP Polyclonal Antibody

    特异性

    CtIP Polyclonal Antibody detects endogenous levels of CtIP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human CtIP around the non-phosphorylation site of S327

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Retinoblastoma Binding Protein 8 (RBBP8)

    别名

    CtIP

    背景

    Rabbit Anti-CtIP Polyclonal Antibody,RBBP8, CTIP, DNA endonuclease RBBP8, CtBP-interacting protein, CtIP, Retinoblastoma-binding protein 8, RBBP-8, Retinoblastoma-interacting protein and myosin-like, RIM, Sporulation in the absence of SPO11 protein 2 homolog, SAE2,The protein encoded by RBBP8 (RB binding protein 8, endonuclease) is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that RBBP8 may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for RBBP8. More transcript variants exist, but their full-length natures have not been determined.,DNA endonuclease RBBP8

    分子量

    observerd band 100kDa

    基因ID

    5932

    UniProt

    Q99708

    途径

    Cell Division Cycle, DNA Damage Repair
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