c-Rel 抗体 (pSer503)
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北京 101111
Quick Overview for c-Rel 抗体 (pSer503) (ABIN7223974)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer503
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原理
- c-Rel (phospho Ser503) Polyclonal Antibody
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特异性
- Phospho-c-Rel (S503) Polyclonal Antibody detects endogenous levels of c-Rel protein only when phosphorylated at S503.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human c-Rel Phospho-Ser503
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- c-Rel
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背景
- Rabbit Anti-c-Rel (phospho Ser503) Polyclonal Antibody,REL, Proto-oncogene c-Rel,REL (REL proto-oncogene, NF-kB subunit) encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of REL is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in REL are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.,Proto-oncogene c-Rel
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基因ID
- 5966
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UniProt
- Q04864
抗原
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