c-Rel 抗体
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北京 101111
Quick Overview for c-Rel 抗体 (ABIN7214334)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- c-Rel Polyclonal Antibody
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特异性
- C-Rel Polyclonal Antibody detects endogenous levels of c-Rel protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human c-Rel around the non-phosphorylation site of S503
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- c-Rel
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背景
- Rabbit Anti-c-Rel Polyclonal Antibody,REL, Proto-oncogene c-Rel,REL encodes REL proto-oncogene, NF-kB subunit that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of REL is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.,Proto-oncogene c-Rel
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分子量
- observerd band 68kDa
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基因ID
- 5966
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UniProt
- Q04864
抗原
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