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c-MET 抗体 (pTyr1356)

This 兔 多克隆 anti-c-MET antibody specifically detects c-MET in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7222452
发货至: 中国
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Quick Overview for c-MET 抗体 (pTyr1356) (ABIN7222452)

抗原

See all c-MET (MET) 抗体
c-MET (MET) (Met Proto-Oncogene (MET))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This c-MET antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pTyr1356

    原理

    Met (phospho Tyr1356) Polyclonal Antibody

    特异性

    Phospho-Met (Y1356) Polyclonal Antibody detects endogenous levels of Met protein only when phosphorylated at Y1356.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Met Phospho-Tyr1356

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    c-MET (MET) (Met Proto-Oncogene (MET))

    别名

    Met

    背景

    Rabbit Anti-Met (phospho Tyr1356) Polyclonal Antibody,MET, Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met,MET encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.,Hepatocyte growth factor receptor

    分子量

    observerd band 160kDa

    基因ID

    4233

    UniProt

    P08581

    途径

    RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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