c-MET 抗体 (pTyr1349)
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Quick Overview for c-MET 抗体 (pTyr1349) (ABIN7213046)
抗原
See all c-MET (MET) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1349
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原理
- Met (phospho Tyr1349) Polyclonal Antibody
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特异性
- Phospho-Met (Y1349) Polyclonal Antibody detects endogenous levels of Met protein only when phosphorylated at Y1349.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Met Phospho-Tyr1349
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亚型
- IgG
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anti-Met Proto-Oncogene (MET) (AA 25-150) antibody
MET 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 743-932) antibodyMET 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5E9C4 unconjugated
anti-Met Proto-Oncogene (MET) (AA 1092-1379) antibodyMET 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) antibodyMET 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 2D12 unconjugated Recombinant Antibody
anti-Met Proto-Oncogene (MET) (C-Term) antibodyMET 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 743-932) antibodyMET 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5E9B7 unconjugated
anti-Met Proto-Oncogene (MET) (Internal Region) antibodyMET 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (Tyr1003) antibodyMET 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 83-209) antibodyMET 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (pTyr1234) antibodyMET 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- c-MET (MET) (Met Proto-Oncogene (MET))
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别名
- Met
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背景
- Rabbit Anti-Met (phospho Tyr1349) Polyclonal Antibody,MET, Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met,MET encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in MET are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of MET are also associated with multiple human cancers.,Hepatocyte growth factor receptor
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分子量
- observerd band 155kDa
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基因ID
- 4233
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UniProt
- P08581
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途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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