KAT2B 抗体 (AA 760-840)
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Quick Overview for KAT2B 抗体 (AA 760-840) (ABIN7216470)
抗原
See all KAT2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 760-840
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原理
- PCAF Polyclonal Antibody
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特异性
- PCAF Polyclonal Antibody detects endogenous levels of PCAF protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human PCAF at AA range: 760-840
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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别名
- PCAF
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背景
- Rabbit Anti-PCAF Polyclonal Antibody,KAT2B, PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Histone acetylase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, P/CAF,CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. Lysine acetyltransferase 2B encoded by KAT2B associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that lysine acetyltransferase 2B plays a direct role in transcriptional regulation.,Histone acetyltransferase KAT2B
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分子量
- observerd band 93kDa
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基因ID
- 8850
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UniProt
- Q92831
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途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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