IRS1 抗体
Quick Overview for IRS1 抗体 (ABIN7215484)
抗原
See all IRS1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IRS-1 Polyclonal Antibody
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特异性
- IRS-1 Polyclonal Antibody detects endogenous levels of IRS-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human IRS-1 around the non-phosphorylation site of S636
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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别名
- IRS-1
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背景
- Rabbit Anti-IRS-1 Polyclonal Antibody,IRS1, Insulin receptor substrate 1, IRS-1,IRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.,Insulin receptor substrate 1
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分子量
- observerd band 170kDa
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基因ID
- 3667
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UniProt
- P35568
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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