BAD 抗体 (pSer134)
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北京 101111
Quick Overview for BAD 抗体 (pSer134) (ABIN7223718)
抗原
See all BAD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer134
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原理
- Bad (phospho Ser134) Polyclonal Antibody
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特异性
- Phospho-Bad (S134) Polyclonal Antibody detects endogenous levels of Bad protein only when phosphorylated at S134.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Bad Phospho-Ser134
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亚型
- IgG
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anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 101-204) antibody
BAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1G5B3 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer136) antibodyBAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer155) antibodyBAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 69-168) antibodyBAD 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibodyBAD 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibodyBAD 适用: 人 ELISA, IHC, DB, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 53-81) antibodyBAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06939 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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别名
- Bad
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背景
- Rabbit Anti-Bad (phospho Ser134) Polyclonal Antibody,BAD, BBC6, BCL2L8, Bcl2 antagonist of cell death, BAD, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, Bcl-XL/Bcl-2-associated death promoter,The protein encoded by BAD (BCL2 associated agonist of cell death) is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of BAD results in two transcript variants which encode the same isoform.,Bcl2 antagonist of cell death
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基因ID
- 572
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UniProt
- Q92934
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途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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