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ATG5 抗体

This 小鼠 单克隆 antibody specifically detects ATG5 in WB, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7201349
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATG5 抗体 (ABIN7201349)

抗原

See all ATG5 抗体
ATG5 (ATG5 Autophagy Related 5 (ATG5))

适用

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人, 小鼠, 大鼠

宿主

  • 93
  • 43
  • 4
  • 1
小鼠

克隆类型

  • 82
  • 59
单克隆

标记

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This ATG5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

3C7
  • 原理

    ATG5 Mouse Monoclonal Antibody (3C7)

    特异性

    The antibody detects endogenous ATG5 protein.

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Recombinant Protein of ATG5

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:50-1:200), IHC-P (1:50-1:300).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ATG5 (ATG5 Autophagy Related 5 (ATG5))

    别名

    ATG5

    背景

    Mouse Anti-ATG5 Mouse Monoclonal Antibody (3C7),Autophagy protein 5, APG5-like, Apoptosis-specific protein,ATG5, also named as APG5L and ASP, belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.,Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)

    基因ID

    9494

    UniProt

    Q9H1Y0

    途径

    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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