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PTEN 抗体

PTEN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7341224
发货至: 中国
  • 抗原 See all PTEN 抗体
    PTEN (Phosphatase and Tensin Homolog (PTEN))
    适用
    • 64
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    宿主
    • 63
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    克隆类型
    • 62
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    多克隆
    标记
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    This PTEN antibody is un-conjugated
    应用范围
    • 40
    • 21
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of Human PTEN
    亚型
    IgG
    Top Product
    Discover our top product PTEN Primary Antibody
  • 应用备注
    ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PTEN (Phosphatase and Tensin Homolog (PTEN))
    别名
    PTEN (PTEN 产品)
    别名
    10q23del antibody, BZS antibody, CWS1 antibody, DEC antibody, GLM2 antibody, MHAM antibody, MMAC1 antibody, PTEN1 antibody, TEP1 antibody, 2310035O07Rik antibody, A130070J02Rik antibody, AI463227 antibody, B430203M17Rik antibody, Mmac antibody, PTENP1 antibody, wu:fc52g04 antibody, zgc:73086 antibody, fa11a08 antibody, fb73f10 antibody, fc83f12 antibody, fd16b10 antibody, fk90e11 antibody, pten antibody, si:bz1g13.4 antibody, wu:fa11a08 antibody, wu:fb73f10 antibody, wu:fc83f12 antibody, wu:fd16b10 antibody, wu:fk90e11 antibody, phosphatase and tensin homolog antibody, phosphatase and tensin homolog L homeolog antibody, phosphatase and tensin homolog A antibody, phosphatase and tensin homolog B antibody, PTEN antibody, Pten antibody, pten.L antibody, ptena antibody, ptenb antibody
    背景

    Background: This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

    Aliases: 10q23del antibody, BZS antibody, DEC antibody, GLM2 antibody, MGC11227 antibody, MHAM antibody, MMAC1 antibody, MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody, Mutated in multiple advanced cancers 1 antibody, Phosphatase and tensin homolog antibody, Phosphatase and tensin like protein antibody, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody, Pten antibody, PTEN_HUMAN antibody, PTEN1 antibody, TEP1 antibody

    UniProt
    P60484
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagy, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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